Incretin Pharmacokinetics
Semaglutide / Tirzepatide Safety
Weight-Based T4 Recalibration
Semaglutide / Tirzepatide Safety
Weight-Based T4 Recalibration
Thyroid & GLP-1 Weight Loss Medication Calculator
Evaluate gastric emptying delays and automatically recalibrate daily levothyroxine dosage as body mass drops during Semaglutide (Ozempic/Wegovy) or Tirzepatide (Mounjaro/Zepbound) therapy.
GLP-1 Recalibration Output
Weight-Based T4 Pharmacokinetics + Gastric Motility Advisory
Dose Reduction Likely Needed
134 mcg/day
Projected Need Based on Weight Loss
Delayed Gastric Emptying Warning
GLP-1 receptor agonists substantially slow gastric emptying. Solid levothyroxine tablets may take longer to reach the small intestine; consider switching to liquid or softgel levothyroxine if your TSH becomes erratic.